Basic Information
VIS ID
TVIS30015701
Fusion event
HIV-EPS15L1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
16500352/16389541 (Hg38)
End
16500432/16389541 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
EPS15L1
miRNAs that regulate target gene
hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-885-3p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-6804-5p ; hsa-mir-185-5p ; hsa-mir-558 ; hsa-mir-1233-3p ; hsa-mir-3192-5p ; hsa-mir-5739 ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-6779-3p ; hsa-mir-3678-3p ; hsa-mir-2467-3p ; hsa-mir-6801-5p ; hsa-mir-4257 ; hsa-mir-759 ; hsa-mir-329-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4803 ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p
Nearest miRNA
hsa-mir-10395/Upstream/939933; hsa-let-7e/Downstream/1892536;
Nearest TSS
ENST00000633603/Upstream/27588; ENST00000587343/Downstream/14204;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/33715, chr19-CpG: 22/Downstream/28406
Upstream sequence
agactctgtttcaaaactaaaaataaaaaaaTGACAACAcagtcgacctgagctataagaagtgctaaagaaagttctttaggctgaaggaaaatgataa
Downstream sequence
tttcctctttctttacaatacccacaatggattaatacaaaaattgtaacagtcttatggagtttctaatgtatttagatgtatgaaattcacatgacgg
Target sequence
tggagggaaaaccaatcttcagtaacaaatgaagagtatcagaaatggtacatatttgggtaaaactaaatgactacttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate