Basic Information
VIS ID
TVIS30015707
Fusion event
HIV-FCHO1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
17875949/17765140 (Hg38)
End
17876141/17765140 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
FCHO1
Nearest miRNA
hsa-mir-10395/Upstream/2315532; hsa-let-7e/Downstream/516937;
Nearest TSS
ENST00000633603/Upstream/2437; ENST00000597076/Downstream/5283;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/17058, chr19-CpG: 24/Downstream/1519
Upstream sequence
gcaataagagcgaaaactctgttttgaaaaaaaaaaaaaaaaaagtgctgggaagggaatgagataggagtgtgagagatcgggcactttctctggggtg
Downstream sequence
gatggcagggtgaggcctcaggggcctgacacacaaatgactttgcaTGAACCTTGTGCccgggcgcggtggctcaagcctttaatcccagcattttggg
Target sequence
ggcccgacctccctgaactgagaccttaatagaaaggggcaggccatggggatgtctgagggacagagacccgggcaagtggctcagccagtgcgaaggccctgagttgacaggcgtggcatgtttacggaagagtgaggaggctggcctggctgcagggcttgggcaacgtggaaaggaagtaggagggga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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