VISDB Viral Integration Site DataBase

VIS ID

TVIS30015709

Fusion event

HIV-PIK3R2 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

18268908/18157705 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-126-3p ; hsa-mir-30c-5p ; hsa-mir-133a-3p ; hsa-mir-296-3p ; hsa-mir-93-5p ; hsa-mir-30d-5p ; hsa-mir-552-3p ; hsa-mir-30a-5p ; hsa-mir-122-5p ; hsa-mir-1295b-5p ; hsa-mir-143-5p ; hsa-mir-1912 ; hsa-mir-3130-5p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-4482-5p ; hsa-mir-504-3p ; hsa-mir-5591-3p ; hsa-mir-564 ; hsa-mir-5693 ; hsa-mir-5698 ; hsa-mir-6499-3p ; hsa-mir-6728-3p ; hsa-mir-891a-3p

Nearest miRNA

hsa-mir-10395/Upstream/2708097; hsa-let-7e/Downstream/124372;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/1626, chr19-CpG: 49/Downstream/3223

Upstream sequence

ggggtgatGCAGTTCTGATGGGAACCCCCTCCCCATTCTGCAGATTGATCCCAGGCCACTCTCAGGGTTGAGTTTCCCAACCCACCGGCCAGAGTGTCAC

Downstream sequence

GAAAACGGGTCATGGTCCTTGGAAGGAAGCTGTTCTGACCCAGGCCGGGATATTTTTCTTTTCTTTCCTTTCAACCACTTTTTTGTTTGCATCAAGAAGG

Target sequence

CCACCTCCACCTCCTCCTTGTCCTTTTCCTTTTTTTTTTTTTTTTTGGCGTTTTCGTTGCAGCTGGGCCTTTCTCCAGCTTGAGGCGCCACCTGGCCCATCACTCAGGGAGGCCCCGCAGGCCCCGGCTTGCCCCTGCTGTGTGCCAGGGCGTCCCCGCCGAGGGCCAGAGCAGCGTCCAATGGTGGCAGACAGCGAGCTGCTGAGGCGGGGATGCTGCACACAAAAGGCCCTGTAGTGCTGGGAAGCCAGGGCT