Basic Information
VIS ID
TVIS30015711
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
18386503/18275693 (Hg38)
End
18386348/18275693 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/2826085; hsa-let-7e/Downstream/6384;
Nearest TSS
ENST00000633603/Upstream/1184; ENST00000595066/Downstream/5236;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/17592, chr19-CpG: 282/Downstream/3857
Nearby gene
IQCN(-1184) ; RPL39P38(+4001) ;
Upstream sequence
CCCTTCTGTGCTGTCAACGAGCTAAACACAAACTGGGAGTTCTCAGGGCAATTGGAGACCGTAGGAGCCCAGTAAGGTGCTGGCCTAGCCTGAGGGTTAC
Downstream sequence
TAGGGACAGGCTTCCGAGGACTGTGCAGCTGAGGCTGGGAGGTGGCGCTCAGCTGCATGACTGGGGGAAGAGTAGCTGGCACAGAACTACAGCTGCAGCC
Target sequence
acaggcatgagccactgcacccagcTCATCCTTTGGATGTTTCATCAGAACAGGTCCCTTCTGTGCTGTCAACGAGCTAAACACAAACTGGGAGTTCTCAGGGCAATTGGAGACCGTAGGAGCCCAGTAAGGTGCTGGCCTAGCCTGAGGGTTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate