Basic Information
VIS ID
TVIS30015712
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
18386498/18275688 (Hg38)
End
18386563/18275688 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/2826080; hsa-let-7e/Downstream/6389;
Nearest TSS
ENST00000633603/Upstream/1179; ENST00000595066/Downstream/5241;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/17587, chr19-CpG: 282/Downstream/3862
Nearby gene
IQCN(-1179) ; RPL39P38(+4006) ;
Upstream sequence
CAGGTCCCTTCTGTGCTGTCAACGAGCTAAACACAAACTGGGAGTTCTCAGGGCAATTGGAGACCGTAGGAGCCCAGTAAGGTGCTGGCCTAGCCTGAGG
Downstream sequence
CTGGGGGAAGAGTAGCTGGCACAGAACTACAGCTGCAGCCGTGCAAAGACCCTGAGGCCAGGAAGGCAGGATATTGGGAATTTGGGTGGAGAGGCTCCTG
Target sequence
GTTACTAGGGACAGGCTTCCGAGGACTGTGCAGCTGAGGCTGGGAGGTGGCGCTCAGCTGCATGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate