Basic Information
VIS ID
TVIS30015716
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
19485664/19374855 (Hg38)
End
19485543/19374855 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/988221; hsa-let-7e/Downstream/60208;
Nearest TSS
ENST00000633603/Upstream/19712; ENST00000448576/Downstream/10971;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/53470, chr19-CpG: 76/Downstream/10288
Nearby gene
GATAD2A(No orient, 10977)
Upstream sequence
gtggtggcctgcacctgcagtcccaggtattcgggaggctgaggtgggaggatcgcttgagctggggaggttgaggctgcagtgagctgtgatcatgcca
Downstream sequence
ctgcactccagcctcagcaacagagcaagaccctgtctctaaaatcagaaagaaaggaagaaaaggcaaaaaGAGGGGAAAAGAAGCCAAGAGAAAGGCT
Target sequence
aaacttaaaaattagctaggcgtggtggcctgcacctgcagtcccaggtattcgggaggctgaggtgggaggatcgcttgagctggggaggttgaggctgcagtgagctgtgatcatgcca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate