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TVIS30015719
Basic Information
VIS ID
TVIS30015719
Fusion event
HIV-GATAD2A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
19546809/19436000 (Hg38)
End
19546603/19436000 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
GATAD2A
miRNAs that regulate target gene
hsa-mir-10a-5p
;
hsa-mir-103a-3p
;
hsa-mir-98-5p
;
hsa-mir-16-5p
;
hsa-mir-615-3p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-1322
;
hsa-mir-5187-5p
;
hsa-mir-1276
;
hsa-mir-4640-5p
;
hsa-mir-4726-5p
;
hsa-mir-548c-3p
;
hsa-mir-4311
;
hsa-mir-211-3p
;
hsa-mir-4648
;
hsa-mir-92b-5p
;
hsa-mir-6739-5p
;
hsa-mir-6733-5p
;
hsa-mir-3153
;
hsa-mir-4745-5p
;
hsa-mir-4328
;
hsa-mir-4481
;
hsa-mir-4681
;
hsa-mir-583
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-92a-2-5p
;
hsa-mir-5010-5p
;
hsa-mir-7111-5p
;
hsa-mir-4525
;
hsa-mir-6870-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-625-5p
;
hsa-mir-6845-5p
;
hsa-mir-6762-5p
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-765
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-4779
;
hsa-mir-4261
;
hsa-mir-3529-3p
;
hsa-mir-1305
;
hsa-mir-1237-3p
;
hsa-mir-1248
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-18a-5p
;
hsa-mir-18b-5p
;
hsa-mir-1908-5p
;
hsa-mir-195-5p
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-3196
;
hsa-mir-3612
;
hsa-mir-3908
;
hsa-mir-3925-3p
;
hsa-mir-424-5p
;
hsa-mir-4305
;
hsa-mir-4443
;
hsa-mir-4466
;
hsa-mir-4706
;
hsa-mir-4735-3p
;
hsa-mir-4749-5p
;
hsa-mir-4777-5p
;
hsa-mir-4787-5p
;
hsa-mir-4802-5p
;
hsa-mir-497-5p
;
hsa-mir-518d-5p
;
hsa-mir-518e-5p
;
hsa-mir-518f-5p
;
hsa-mir-519a-5p
;
hsa-mir-519b-5p
;
hsa-mir-519c-5p
;
hsa-mir-520c-5p
;
hsa-mir-522-5p
;
hsa-mir-523-5p
;
hsa-mir-526a
;
hsa-mir-589-3p
;
hsa-mir-6502-3p
;
hsa-mir-650
;
hsa-mir-663a
;
hsa-mir-6730-5p
;
hsa-mir-6753-5p
;
hsa-mir-675-5p
;
hsa-mir-6787-5p
;
hsa-mir-6816-5p
;
hsa-mir-6827-5p
;
hsa-mir-6838-5p
;
hsa-mir-6868-3p
;
hsa-mir-744-5p
;
hsa-mir-766-3p
Nearest miRNA
hsa-mir-10395/Upstream/842; hsa-let-7e/Downstream/963272;
Nearest TSS
ENST00000633603/Upstream/8473;
ENST00000444839/Downstream/21112;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/29426
,
chr19-CpG: 26/Downstream/65129
Upstream sequence
TCTGGGACGTTGGCGTTCATTGGTTAGCACTGTATTGTTTCATACCTCAGAGATCAGTAGAAATTTGTTTCCTCCGACTGTCCCCATTGTGGAAGGTAGC
Downstream sequence
TGAGGCAAAACTCAGGAAATCTGAAATTTTGCTATGTAATTCCAGGGGTTAGAGACATTTTAGAAATGCCAGTATGTTCCAGAAACCTTGCTTGGAAACA
Target sequence
agccgagatcgtgccacttcactccagtctgggcATAAGATAAAAATAATTGTATTTCATCGTGTGACTGCTTTTTATGTCACCATCTGTATTGGTGAAGACAGTGTCTGGGACGTTGGCGTTCATTGGTTAGCACTGTATTGTTTCATACCTCAGAGATCAGTAGAAATTTGTTTCCTCCGACTGTCCCCATTGTGGAAGGTAGC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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