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TVIS30015722
Basic Information
VIS ID
TVIS30015722
Fusion event
HIV-ZNF43 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
22026326/21843524 (Hg38)
End
22026056/21843524 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF43
miRNAs that regulate target gene
hsa-mir-6510-3p
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-6729-5p
;
hsa-mir-4649-5p
;
hsa-mir-661
;
hsa-mir-4486
;
hsa-mir-4696
;
hsa-mir-766-3p
;
hsa-mir-939-3p
;
hsa-mir-6849-3p
;
hsa-mir-451b
;
hsa-mir-508-5p
;
hsa-mir-4432
;
hsa-mir-7703
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-1292-3p
;
hsa-mir-1273g-3p
;
hsa-mir-640
;
hsa-mir-378a-5p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-665
;
hsa-mir-6825-5p
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-6889-5p
;
hsa-mir-6777-5p
;
hsa-mir-4768-3p
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-4655-5p
;
hsa-mir-34b-3p
Nearest miRNA
hsa-mir-10395/Upstream/1444170; hsa-let-7e/Downstream/13279176;
Nearest TSS
ENST00000633603/Upstream/1877;
ENST00000596471/Downstream/8444;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/7499
,
chr19-CpG: 42/Downstream/8068
Nearby gene
ZNF43
(No orient, 7356)
Upstream sequence
tcaccatctcaatgtagatgaatccatgcataacaacctcaatctcttctgcggactgtgtctcttagtaaaatcatagccttggccaggcgtggtgcct
Downstream sequence
cacacctgtaaccccagcactttgggaggccaaggcaggtggatcacctgaggtcaggagtagagaccagcctggccaacatggcaaaatctcatctcta
Target sequence
tctgtgtactgggcccaggcaggagagtcaaatcgctcacattctgagcagaggtatgtgtcacaatcacacctgcagaaagacccagAAATCAGATAAAACAGTTCTTCACGTGTCTTCATtctaggtatgagtcaataccatttggatattgggtctaagtacacaagtcaccatctcaatgtagatgaatccatgcataacaacctcaatctcttctgcggactgtgtctcttagtaaaatcatagccttgg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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