Basic Information
VIS ID
TVIS30015729
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
34721511/34230606 (Hg38)
End
34721444/34230606 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/13831252; hsa-let-7e/Downstream/892094;
Nearest TSS
ENST00000633603/Upstream/9256; ENST00000585833/Downstream/23931;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/57451, chr19-CpG: 97/Downstream/23707
Nearby gene
LSM14A(No orient, 1091)
Upstream sequence
TCAGCATTGTGGAAACATTACCACATAGGAGTTAGGGCTTCATCCTGTTCTCTGTcagtgcttcacaaatctctgatcagaatctaccaaggagcatttt
Downstream sequence
taagtacagattcccaggcccagagagtgattctgaagttccctagtacagcagaacccaacctttttggcaccagggactggtttcaccaaagacagtt
Target sequence
AGGGCTTCATCCTGTTCTCTGTcagtgcttcacaaatctctgatcagaatctaccaaggagcatttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate