Basic Information
VIS ID
TVIS30015732
Fusion event
HIV-FXYD7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
35640612/35149709 (Hg38)
End
35640382/35149709 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
FXYD7
Nearest miRNA
hsa-mir-10395/Upstream/26945; hsa-let-7e/Downstream/195804;
Nearest TSS
ENST00000633603/Upstream/6430; ENST00000392218/Downstream/5021;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5984, chr19-CpG: 36/Downstream/4985
Upstream sequence
atatctcaacaaatacttagcgggcacaggctctatttctggcaatgttccaagcagctggagacactgcaatgaaccacacagacaagaattcaagaat
Downstream sequence
gcaagaattcctgccctcctcctggaccttccactcaatgggaaagggacagatactcaagaaaacaaaatatgaaaattatatattagacaagaatatt
Target sequence
TCAGCTGGTGTCGCATGACTTGTTTTTGAGGGGGATTGTTTCTTTAATGTTTTATCACAATACGAAAGTCAACTCCTTGCTGGTAGAGGCCTGGACCACTACTGGTACAGAGTGAGTGCTCCATAAattcatatctcaacaaatacttagcgggcacaggctctatttctggcaatgttccaagcagctggagacactgcaatgaaccacacagacaagaattcaagaat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate