Basic Information
VIS ID
TVIS30015749
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
40468638/39962731 (Hg38)
End
40468511/39962731 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/132929; hsa-let-7e/Downstream/319812;
Nearest TSS
ENST00000633603/Upstream/28105; ENST00000596386/Downstream/8274;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/38027, chr19-CpG: 39/Downstream/7873
Nearby gene
PSMC4(No orient, 8434)
Upstream sequence
agatcgtgccattgcactccagcctgggggacagagtgagactctgtctcaaaaaaaaaaaaagcagaaaaaaaagcagacattaagatccagttgtttt
Downstream sequence
ccatcaagctggacattaaagagatttgcaaaaatgcaaaacaatgctactcttctcTgaccataatagaattaaagtagaaatcaattaacagaaagat
Target sequence
ctgagaggcagaggttgcagcaagccaagatcgtgccattgcactccagcctgggggacagagtgagactctgtctcaaaaaaaaaaaaagcagaaaaaaaagcagacattaagatccagttgtttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate