Basic Information
VIS ID
TVIS30015752
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
42048193/41541831 (Hg38)
End
42048147/41541831 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/1171924; hsa-let-7e/Downstream/327796;
Nearest TSS
ENST00000633603/Upstream/6264; ENST00000601116/Downstream/3361;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/19490, chr19-CpG: 28/Downstream/23166
Nearby gene
CEACAM21(No orient, 34337)
Upstream sequence
ggagttgtttatgacctgaaaatatttactaagggcagtatttgacctgtataatttaaaccaaatgtctaaattctgaagatgttctaattttacttta
Downstream sequence
ctaataattttaaagcatgctttattttttaaagatttttaaagtcaggtgaattaaaagggatttgagttaaagtttttgtattttctgagaaaatatt
Target sequence
tttaaaccaaatgtctaaattctgaagatgttctaattttacttta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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