Basic Information
VIS ID
TVIS30015759
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
45112447/44609129 (Hg38)
End
45112501/44609129 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/2257924; hsa-let-7e/Downstream/44557;
Nearest TSS
ENST00000633603/Upstream/72516; ENST00000592507/Downstream/4501;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/108335, chr19-CpG: 63/Downstream/34645
Nearby gene
IGSF23(No orient, 4492)
Upstream sequence
aaaGGGTAgccaagtgcagaggctcaggcctgtaatcccggcactttgggaagccaaagcaggaggatcacttgtgcccaggagtttgagaccagcctgg
Downstream sequence
ggtggtgtgtgctgtagtcctagctactcggggggatgaggcaggaagatcacttgagccaagaggtcaaggctgcagtgagctgtggtcacaccaccgc
Target sequence
gcaacataggaagatcccaactctacaaaaaaatttttttaattagtcggtcat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate