Basic Information
VIS ID
TVIS30015762
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
46167990/45664732 (Hg38)
End
46167723/45664732 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/25645; hsa-let-7e/Downstream/10196;
Nearest TSS
ENST00000633603/Upstream/19103; ENST00000591322/Downstream/3512;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/19049, chr19-CpG: 17/Downstream/6382
Nearby gene
GIPR(No orient, 3511)
Upstream sequence
CTGGCGACTGTCATGATGAGACCATGTGAGGCTATGGGTTAGTGTGCAATTGTGACACGATGGTGTGTGTGACCCTGTGTGCACCTGTGTGACTGTGCGT
Downstream sequence
GACTGTGGGAGGTGGGATTGCAGGGTGTGACAAGTCACTGTGACGTGCACAGCTATGGGACAGTGAGGTTGTGTGCGTGACATGTATATGACTGTATGTG
Target sequence
ATGATTAATGTGCAGGAATTGGAGTTTGTATTAACAGGAGATGAGAGCTGGGAGCTGGGACTGGGCTCTGAGCCTGTCCCCCACCCCCAGTCACGTACAGATGTTCCCCATATTTAGGGCAAAGGAACAGACTGGAAGTAGAGACAGCAGAGAATGTGTGTGATTCACTGGCGACTGTCATGATGAGACCATGTGAGGCTATGGGTTAGTGTGCAATTGTGACACGATGGTGTGTGTGACCCTGTGTGCACCTGT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate