Basic Information
VIS ID
TVIS30015764
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47087033/46583776 (Hg38)
End
47086992/46583776 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/564727; hsa-let-7e/Downstream/125506;
Nearest TSS
ENST00000633603/Upstream/87278; ENST00000602169/Downstream/17149;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/69915, chr19-CpG: 122/Downstream/16753
Upstream sequence
ctaaaaaataaaaagaaaaGTTTAAAAAAAAGTTTTTTAAGTGAAAGACAAATCagatcaatgaaaatgaacacatgatatacaaaaacatatgggatac
Downstream sequence
actaaagtagtgcttggaggaaaatttacagctgcaaattgcctatattgaaagagaaaaatggtctcaaatcaataacctaatcttccatcttaagaaa
Target sequence
aatgaaaatgaacacatgatatacaaaaacatatgggatac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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