Basic Information
VIS ID
TVIS30015765
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47416639/46913382 (Hg38)
End
47416716/46913382 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/204028; hsa-let-7e/Downstream/313560;
Nearest TSS
ENST00000633603/Upstream/62390; ENST00000596593/Downstream/5294;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/51837, chr19-CpG: 40/Downstream/90667
Nearby gene
ARHGAP35(No orient, 5293)
Upstream sequence
GTTGGAAGAGTGATACACACACTTCCAGGCGTATGCTGATAGAGCTGTTGACAGTATGAACTTTCCCAGTCATAGTAAATCTGGGATCACGGTGGCATTT
Downstream sequence
AAGAAAACACCCTCCTTCTACCTTCCAGTTGCGGCACTCTGGTGGGGACCTTGTGTCTTGGTTAAACAAATCACAAACAACTCTAGATGCTTGGTGACAG
Target sequence
CTAGGTCCTACAAAAATGTGTGCTATCTTGGGAATGTTACCACTTCTTGCCCTGAGTGTTTCATAGAGGTGTTAAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate