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TVIS30015767
Basic Information
VIS ID
TVIS30015767
Fusion event
HIV-ZC3H4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47603706/47100449 (Hg38)
End
47603442/47100449 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZC3H4
miRNAs that regulate target gene
hsa-mir-423-3p
;
hsa-mir-331-3p
;
hsa-mir-183-5p
;
hsa-mir-34a-5p
;
hsa-mir-26b-5p
;
hsa-mir-320a
;
hsa-mir-218-5p
;
hsa-mir-5706
;
hsa-mir-4782-5p
;
hsa-mir-516b-5p
;
hsa-mir-1299
;
hsa-mir-6077
;
hsa-mir-4455
;
hsa-mir-6128
;
hsa-mir-875-3p
;
hsa-mir-6514-5p
;
hsa-mir-4802-5p
;
hsa-mir-8076
;
hsa-mir-3163
;
hsa-mir-7-5p
;
hsa-mir-663b
;
hsa-mir-7155-3p
;
hsa-mir-3136-3p
;
hsa-mir-6778-3p
;
hsa-mir-1827
;
hsa-mir-361-3p
;
hsa-mir-4650-5p
;
hsa-mir-3065-3p
;
hsa-mir-6513-3p
;
hsa-mir-3677-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6510-5p
;
hsa-mir-4690-5p
;
hsa-mir-6165
;
hsa-mir-6871-3p
;
hsa-mir-1224-5p
;
hsa-mir-3650
;
hsa-mir-3915
;
hsa-mir-4436a
;
hsa-mir-4689
;
hsa-mir-4725-5p
;
hsa-mir-4751
;
hsa-mir-5000-3p
;
hsa-mir-5004-5p
;
hsa-mir-504-5p
;
hsa-mir-6858-5p
;
hsa-mir-7978
Nearest miRNA
hsa-mir-10395/Upstream/391095; hsa-let-7e/Downstream/126493;
Nearest TSS
ENST00000633603/Upstream/5962;
ENST00000594526/Downstream/11780;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/51570
,
chr19-CpG: 20/Downstream/10702
Upstream sequence
GAACAAATGTGCTCTGTCTCCTTTTCTTCAGCATTCTCAGGTGTCATCATAGCCTGCTCTGTGACATCATGCCATTTCCATGGTAACGTGCCTACGCCAC
Downstream sequence
GGCAACCACCCAAGTGAGACACAAAACTGGCAAAGAGAAGTCCAGGCATCAGCATCTGTACCCTGTACCCTACACCCTCACTTCAACATAAGACAGTCTA
Target sequence
AAGAAAGGCCCGAGACCTTCCCTTGAGTTAGGACGTAATGAAGCAGCCATAGGGGAAACCTCACGGAGGGATTTTCAGAGCCAGGAAATTCTTGAAATAAACCTCTGGGTCTTGCACATGCTTTTCAGTGTCCTTACTACCTAGGTTCATCAACCAGAAACCAAGAACAAATGTGCTCTGTCTCCTTTTCTTCAGCATTCTCAGGTGTCATCATAGCCTGCTCTGTGACATCATGCCATTTCCATGGTAACGTGC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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