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TVIS30015773
Basic Information
VIS ID
TVIS30015773
Fusion event
HIV-CARD8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
48751064/48247807 (Hg38)
End
48751104/48247807 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
CARD8
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-15a-5p
;
hsa-mir-375
;
hsa-mir-629-5p
;
hsa-mir-4793-5p
;
hsa-mir-4724-5p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-6499-3p
;
hsa-mir-6086
;
hsa-mir-2467-3p
;
hsa-mir-377-5p
;
hsa-mir-4487
;
hsa-mir-1827
;
hsa-mir-558
;
hsa-mir-3160-3p
;
hsa-mir-665
;
hsa-mir-4257
;
hsa-mir-4459
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-4695-5p
;
hsa-mir-6818-3p
;
hsa-mir-548s
;
hsa-mir-4684-5p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-3926
;
hsa-mir-3190-5p
;
hsa-mir-5699-3p
;
hsa-mir-4421
;
hsa-mir-8073
;
hsa-mir-221-5p
;
hsa-mir-339-5p
;
hsa-mir-4698
;
hsa-mir-10b-5p
;
hsa-mir-10a-5p
;
hsa-mir-6732-3p
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-548c-3p
;
hsa-mir-6079
;
hsa-mir-7977
;
hsa-mir-3165
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-3202
;
hsa-mir-4533
;
hsa-mir-3656
;
hsa-mir-6087
;
hsa-mir-4493
;
hsa-mir-383-3p
;
hsa-mir-194-5p
;
hsa-mir-219a-1-3p
;
hsa-mir-3613-3p
;
hsa-mir-3672
;
hsa-mir-431-5p
;
hsa-mir-4635
;
hsa-mir-4668-5p
;
hsa-mir-4725-5p
;
hsa-mir-4786-5p
;
hsa-mir-4797-5p
;
hsa-mir-555
;
hsa-mir-661
;
hsa-mir-6861-5p
;
hsa-mir-6864-3p
;
hsa-mir-769-5p
Nearest miRNA
hsa-mir-10395/Upstream/1020786; hsa-let-7e/Downstream/762099;
Nearest TSS
ENST00000633603/Upstream/6744;
ENST00000602172/Downstream/1807;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/43603
,
chr19-CpG: 53/Downstream/23491
Upstream sequence
CGCAAAATTTTATATATATATACTATACTTTCATGACACTATGTTATTGtatatatatatatatatatataCACACACACACAATGCTTCCATTTGTTTT
Downstream sequence
ttttaacattaaaataCACATGATTTTTACCATTTGTGATACACATTGTATCATATGTATTCTCAATTGAAATTTCAATTAAAATTCAGTTACCACTCAT
Target sequence
GATGTCACACAAGCaaaattaaattacactaaattttaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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