Basic Information
VIS ID
TVIS30015774
Fusion event
HIV-BCAT2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49301554/48798297 (Hg38)
End
49301253/48798297 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
BCAT2
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10395/Upstream/1571276; hsa-let-7e/Downstream/211609;
Nearest TSS
ENST00000633603/Upstream/754; ENST00000600406/Downstream/8777;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2809, chr19-CpG: 21/Downstream/1301
Upstream sequence
cctggcTCCAAAACCGTTTCTGTtgtcacctcctcgagaggtgtttccagacctccaggctgggtgctggaccttccctggactcccccagtgaactggg
Downstream sequence
ctacctggatgactttctgagtctctctcccAGAGATAGCCTCTCCCCTCAGCTGCTAACAAGCCTCCCATGGCTCCCCAGTGCCCCAGGACAAGACCCT
Target sequence
atttatatttatatgcccgcctcagccccccaaagtgctgggattacaagagtgagccacagcgcccggccTTACtttttatatttttagtagagacggggtttcaccatgttggccaggctggtctcaaactcctgacctcaagtgatccgcctacctcggcctcccaaagtgctgggattacaagcgtgagctaccgcgcctggcTCCAAAACCGTTTCTGTtgtcacctcctcgagaggtgtttccagacct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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