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TVIS30015775
Basic Information
VIS ID
TVIS30015775
Fusion event
HIV-NUCB1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49423780/48920523 (Hg38)
End
49423729/48920523 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
NUCB1
miRNAs that regulate target gene
hsa-mir-30a-5p
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-484
;
hsa-mir-92a-3p
;
hsa-mir-4762-3p
;
hsa-mir-1303
;
hsa-mir-744-3p
;
hsa-mir-4303
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-6761-5p
;
hsa-mir-4329
;
hsa-mir-4251
;
hsa-mir-4781-3p
;
hsa-mir-483-5p
;
hsa-mir-6131
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-3663-5p
;
hsa-mir-335-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-3152-5p
;
hsa-mir-3942-3p
;
hsa-mir-6881-3p
;
hsa-mir-6836-3p
;
hsa-mir-1248
;
hsa-mir-877-3p
;
hsa-mir-3614-3p
;
hsa-mir-1245b-3p
;
hsa-mir-1293
;
hsa-mir-3199
;
hsa-mir-363-5p
;
hsa-mir-365a-5p
;
hsa-mir-365b-5p
;
hsa-mir-4483
;
hsa-mir-4515
;
hsa-mir-4648
;
hsa-mir-5008-5p
;
hsa-mir-6089
;
hsa-mir-6730-5p
;
hsa-mir-6733-3p
;
hsa-mir-6745
;
hsa-mir-6748-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-8052
;
hsa-mir-1273e
;
hsa-mir-1537-3p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-2467-3p
;
hsa-mir-3612
;
hsa-mir-3664-3p
;
hsa-mir-377-5p
;
hsa-mir-4257
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4499
;
hsa-mir-4523
;
hsa-mir-455-3p
;
hsa-mir-4649-3p
;
hsa-mir-4695-5p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-510-5p
;
hsa-mir-512-5p
;
hsa-mir-545-5p
;
hsa-mir-5690
;
hsa-mir-6086
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-6516-5p
;
hsa-mir-665
;
hsa-mir-6808-5p
;
hsa-mir-6857-3p
;
hsa-mir-6893-5p
;
hsa-mir-873-3p
;
hsa-mir-940
;
hsa-mir-143-3p
;
hsa-mir-31-3p
;
hsa-mir-4735-5p
;
hsa-mir-4770
;
hsa-mir-4775
;
hsa-mir-590-3p
;
hsa-mir-6088
Nearest miRNA
hsa-mir-10395/Upstream/1693502; hsa-let-7e/Downstream/89383;
Nearest TSS
ENST00000633603/Upstream/1523;
ENST00000523250/Downstream/13159;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/20162
,
chr19-CpG: 37/Downstream/12915
Upstream sequence
tcaggtgatcctccttccttagcctcctgagtaactgggactacaggcacataccaccatgcccagctaatctaggtctctgttttatttatttatttat
Downstream sequence
ttgtttgtttatttTTCAATacagagttttgctcttgttgcccaggctgtagtgcaatggtgcattctcagctcattgcaacctccacctcccaggttca
Target sequence
cataccaccatgcccagctaatctaggtctctgttttatttatttatttat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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