Basic Information
VIS ID
TVIS30015776
Fusion event
HIV-NOSIP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50079055/49575798 (Hg38)
End
50079020/49575798 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
NOSIP
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-124-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10395/Upstream/74930; hsa-let-7e/Downstream/106319;
Nearest TSS
ENST00000633603/Upstream/15107; ENST00000596877/Downstream/3480;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/18880, chr19-CpG: 17/Downstream/4702
Upstream sequence
cataaaagcagccacagacacacaaacgggcatggctgtgttccaataaaactttacttttagactctgacacggaatcacatataattgtcataggtca
Downstream sequence
ccaaattcattcttttggttttttccagttatgtaaaaacgttaaaaaccaggccaggcgcagtggctcacgcctgtaatcccagcactttgggaggcca
Target sequence
tctgacacggaatcacatataattgtcataggtca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate