Basic Information
VIS ID
TVIS30015778
Fusion event
HIV-NOSIP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50081319/49578062 (Hg38)
End
50081344/49578062 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
NOSIP
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-124-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10395/Upstream/77194; hsa-let-7e/Downstream/104055;
Nearest TSS
ENST00000633603/Upstream/17371; ENST00000596877/Downstream/1216;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/21144, chr19-CpG: 17/Downstream/2438
Upstream sequence
atagggaatgactgctaatgagtaccagggtttctttttgggtgatgaaaatattcttaaaatgatagtgttgatggttgcacaactctgtcaacgtact
Downstream sequence
aatgggtgaactatatgttaggtaaatcatatcccactaatgctttttttttttgagagggagttatgctcttttgcccaggctggagtgaagtggcatg
Target sequence
aaacaccactgaattgtatattttc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate