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TVIS30015780
Basic Information
VIS ID
TVIS30015780
Fusion event
HIV-PRR12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50126880/49623623 (Hg38)
End
50126718/49623623 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
PRR12
miRNAs that regulate target gene
hsa-mir-744-5p
;
hsa-mir-615-3p
;
hsa-mir-320a
;
hsa-mir-34a-5p
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-mir-6763-5p
;
hsa-mir-3150a-3p
;
hsa-mir-6515-5p
;
hsa-mir-6778-5p
;
hsa-mir-1233-5p
;
hsa-mir-6848-5p
;
hsa-mir-7847-3p
;
hsa-mir-6846-5p
;
hsa-mir-6825-5p
;
hsa-mir-939-5p
;
hsa-mir-1343-5p
;
hsa-mir-3175
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-6797-5p
;
hsa-mir-149-3p
;
hsa-mir-1249-5p
;
hsa-mir-766-5p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4419a
;
hsa-mir-4510
;
hsa-mir-194-3p
;
hsa-mir-6805-5p
;
hsa-mir-4786-5p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-4666b
;
hsa-mir-5011-3p
;
hsa-mir-6076
;
hsa-mir-6797-3p
;
hsa-mir-6807-5p
Nearest miRNA
hsa-mir-10395/Upstream/122755; hsa-let-7e/Downstream/58494;
Nearest TSS
ENST00000633603/Upstream/3174;
ENST00000601038/Downstream/2816;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/7404
,
chr19-CpG: 68/Downstream/16343
Upstream sequence
cgcgaggctgaggcagaataatggtgtgaacccgggaggcggagcttgcagtgagccaaggtcgcgccactgcactccagcctgggcgacagagcgagac
Downstream sequence
tttgtcttaaaaaaaaaaaaaaaagaaTTCTGGGGTAGATGGGATGGTTAGGATAGGGCTGAGAATTCTGGGATAGATGGTTAGGATGGGGCCAATAATT
Target sequence
ctactaaaaatacacaaaaaattagccgggtgtggtggtgggtgcctgtagtcccagctactcgcgaggctgaggcagaataatggtgtgaacccgggaggcggagcttgcagtgagccaaggtcgcgccactgcactccagcctgggcgacagagcgagac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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