Basic Information
VIS ID
TVIS30015791
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
54701378/54197514 (Hg38)
End
54701149/54197514 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/215117; hsa-mir-10394/Downstream/84595;
Nearest TSS
ENST00000633603/Upstream/6261; ENST00000460761/Downstream/2457;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5868, chr19-CpG: 53/Downstream/3202
Nearby gene
TSEN34(No orient, 2984)
Upstream sequence
CAGGGTGAGGCCAGATCTCATcagttgacccttgagcaacatgggtctgaactgctcgggtccacttttatgcagattGAAAAAAGTAaaggttacacag
Downstream sequence
agcatgcctgcctctcctgctttgccttttacctcctccacctctggcaccctgagacagcaagaccaaaccctcctcttctttctgcacctctgcctac
Target sequence
CCCGTGCTCCTTTCAGAGAGGAAGGGCTAGAGGGCTCCAGCCTGAGTGAGAGAGAGAGAGGAGGAAGCATGAGGGGTTTGTGGAAGAGGGCCTGGTGCCATATGACTGGACCATGCTTCTGAAGAGGATCAGGGTGAGGCCAGATCTCATcagttgacccttgagcaacatgggtctgaactgctcgggtccacttttatgcagattGAAAAAAGTAaaggttacacag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate