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Viral Integration Site DataBase
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TVIS30015792
Basic Information
VIS ID
TVIS30015792
Fusion event
HIV-U2AF2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
56169789/55658423 (Hg38)
End
56169763/55658423 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
U2AF2
miRNAs that regulate target gene
hsa-mir-455-3p
;
hsa-mir-671-5p
;
hsa-mir-542-5p
;
hsa-mir-615-3p
;
hsa-mir-92b-3p
;
hsa-mir-324-3p
;
hsa-mir-210-3p
;
hsa-mir-196a-5p
;
hsa-mir-92a-3p
;
hsa-mir-588
;
hsa-mir-548s
;
hsa-mir-3163
;
hsa-mir-3187-3p
;
hsa-mir-4435
;
hsa-mir-4701-5p
;
hsa-mir-423-5p
;
hsa-mir-486-3p
;
hsa-mir-3184-5p
;
hsa-mir-4688
;
hsa-mir-3064-3p
;
hsa-mir-6743-5p
;
hsa-mir-4698
;
hsa-mir-6721-5p
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-6888-5p
;
hsa-mir-4529-5p
;
hsa-mir-8063
;
hsa-mir-1226-5p
;
hsa-mir-1252-5p
;
hsa-mir-185-3p
;
hsa-mir-3065-5p
;
hsa-mir-3144-5p
;
hsa-mir-3178
;
hsa-mir-3529-3p
;
hsa-mir-3687
;
hsa-mir-4442
;
hsa-mir-4486
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4505
;
hsa-mir-4508
;
hsa-mir-4721
;
hsa-mir-4743-5p
;
hsa-mir-4751
;
hsa-mir-5001-5p
;
hsa-mir-5787
;
hsa-mir-6089
;
hsa-mir-6758-5p
;
hsa-mir-6762-5p
;
hsa-mir-6781-5p
;
hsa-mir-6845-5p
;
hsa-mir-6856-5p
;
hsa-mir-762
Nearest miRNA
hsa-let-7e/Upstream/270181; hsa-mir-10394/Downstream/2676265;
Nearest TSS
ENST00000633603/Upstream/3314;
ENST00000592867/Downstream/785;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/2532
,
chr19-CpG: 18/Downstream/6846
Upstream sequence
TCCATCTTGAAGGGCCGGTCTCTCTTCAGGGGTTGAAGGGTCTGGTGAGAGCAGAGGTTTCTGTGGTTTTGCCAGTGAGGCTCCGTTCCTAGTGGCTACC
Downstream sequence
TCAGGCAAATAGAGGGTTGAGGGAGCCTGCTGGAGGCTGGCAGAGATACCCGCCCCTACTCACGCCTTTACAGTCTCTTCAGTACTTGGCTTTGAAGGGA
Target sequence
GTGAGGCTCCGTTCCTAGTGGCTACC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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