Basic Information
VIS ID
TVIS30015795
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
58292426/57781058 (Hg38)
End
58292237/57781058 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/2392816; hsa-mir-10394/Downstream/553630;
Nearest TSS
ENST00000633603/Upstream/11362; ENST00000594328/Downstream/32346;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/10940, chr19-CpG: 62/Downstream/5046
Nearby gene
ZNF586(No orient, 442)
Upstream sequence
gcacatctggtcacagaattattccatattgattgttgttgtgttgtgtgacagacaatagaggaaaagtttatttttttctacacaTACGCTATGGCTT
Downstream sequence
CCCTTCTATTATTCCATATCTTTCAACTCCTGCCATACTATTTCTTTCTCTCCAAGTTTTTGTTCTTCCTCAGAGTTCCCATAAATGGAAAGGATACGCA
Target sequence
atctgcaggtagataatgactgagttgaactggaggacccccagcttgtgtccacgggaggattgcttggtgtgtgtggaaaacaccctgcacatctggtcacagaattattccatattgattgttgttgtgttgtgtgacagacaatagaggaaaagtttatttttttctacacaTACGCTATGGCTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate