Basic Information
VIS ID
TVIS30015797
Fusion event
HIV-ZNF274 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
End
58708346/58197194 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7e/Upstream/2808952; hsa-mir-10394/Downstream/137494;
Upstream sequence
CCCTTATTCAGCATCACAGAAGTTGTACTAGAGATTACCTGAGAACATAGGGCTGGGAAGCCTTCGGGTGTCCCAGAACTCACTGGCAAGGATCCCTCTC
Downstream sequence
TGAACACAGCATTTTGGGAACCCCTTCAGTAGGAGTCCTCATTGTTTTCAGCATCAGAGGACTCATATGGGCAAACATCCTGTGAATGAAATCTGTGCAG
Target sequence
TCAGTCTTATCTTGAGAGGATTCATACTGGAAAAGTTCTTACATTGAGTATTACATCTAAGAGCTTCTGAAACCATGAGAATATAATTGCTGTGGGAAAGGTTTTATGCATAGCTCCCTTATTCAGCATCACAGAAGTTGTACTAGAGATTACCTGAGAACATAGGGCTGGGAAGCCTTCGGGTGTCCCAGAACTCACTGGCAAGGATCCCTCTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate