Basic Information
VIS ID
TVIS30015801
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
9874913/9734784 (Hg38)
End
9875067/9734784 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-7158/Upstream/3084345; hsa-mir-10b/Downstream/457830;
Nearest TSS
ENST00000437798/Upstream/60761; ENST00000497182/Downstream/35557;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/103351, chr2-CpG: 76/Downstream/108350
Nearby gene
YWHAQ(No orient, 103807)
Nearest cancer related gene
YWHAQ(OG, No orient, 103807)
Upstream sequence
gacctttatcactatttctattttggatttcatggagtcttagtataataaaaatattaaaataaaacatgtaaacactagaaagaaaaaaattgccatt
Downstream sequence
TTTCTAGAATACCCTTTCAAATATATTCTATCTATCTTCAGACTTAATGATTATACTCCAAGACCCCCTGTGTGATTCTTTTACAATCACACCCCCAGCA
Target sequence
attcacaaattacataattgtcttcaaagaaaattcaaaataaactacaaaCCTACTCACATGGTAAAAATTTAAATAAGTATTGAGTGAAAATTAACTTCCCTCTTATCCTGGTCACCAGCTCTCCTTCCCCGCAGCAACTACTGTTACTGAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate