Basic Information
VIS ID
TVIS30015803
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
14904684/14764560 (Hg38)
End
14904562/14764560 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3125/Upstream/2027116; hsa-mir-10b/Downstream/4583869;
Nearest TSS
ENST00000437798/Upstream/129064; ENST00000438178/Downstream/143104;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/128875, chr2-CpG: 27/Downstream/796455
Nearby gene
LRATD1(No orient, 124516)
Upstream sequence
gctttggtcttggcaagaaactgcaattttgagtctctgttttatcatcagtgaaataaaggggcagaatgagatgattcctattctttctactcagaac
Downstream sequence
tgctacaaatgtaagtaaaataCAATGCAACTTGGGGGAAAGGAATCAATAACTTAAATTATTGGGAAAAAAAAAAGCCAGCAGAGTAATTAATTTAAAA
Target sequence
ctggattctacaactcaccttggctttggtcttggcaagaaactgcaattttgagtctctgttttatcatcagtgaaataaaggggcagaatgagatgattcctattctttctactcagaac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate