Basic Information
VIS ID
TVIS30015805
Fusion event
HIV-RBKS integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
28080485/27857618 (Hg38)
End
28080616/27857618 (Hg38)
Orient
+
Location type
Intronic
Target gene
RBKS
Nearest miRNA
hsa-mir-1301/Upstream/2528897; hsa-mir-10b/Downstream/138749;
Nearest TSS
ENST00000437798/Upstream/14457; ENST00000492702/Downstream/32323;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/85541, chr2-CpG: 78/Downstream/32575
Upstream sequence
CCCAGATTCTTTTCAGATCTAAGATACAGCATTAGAAGAAAATGACTTAGAGATGAGTAAATCACCGGTTATTACAAGAAGTTTCCAAAAGCTGTGTTGC
Downstream sequence
GCAGCATTAAGTTATTTGAGAACTGCTACTTCCCAGAGGATTCAATGAGGTAGAAATTAGTATAAAGGACAAGGGAGACTATTCTCTGTTATTTAGATCT
Target sequence
TGCGGTGAAACCTGCTAAAAACAAGGTGACTCATGCTGTTGTTTAGAAGCTGGATGACAGAAACCCATTGGAGTACGCTAATTTCCCTCACTTCTCACACCCCAGTTACAAACTCATTACATTCAGGGAAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate