Basic Information
VIS ID
TVIS30015807
Fusion event
HIV-BABAM2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
28176256/27953389 (Hg38)
End
28176189/27953389 (Hg38)
Orient
-
Location type
Intronic
Target gene
BABAM2
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1301/Upstream/2624668; hsa-mir-10b/Downstream/42978;
Nearest TSS
ENST00000437798/Upstream/58769; ENST00000460736/Downstream/357070;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/62492, chr2-CpG: 302/Downstream/436708
Upstream sequence
tcctaccccaggctcccaagtagctggggtgggaggagcctgagctcctcgcctggctaatttttttactttgtatagagacagggtctacctgtgttgc
Downstream sequence
ccaggatggtcttgaattcttgggctcaagtgatcctcctgccttggcctaccacagtgctgggattacaggcatgaaccaccgtagtgacagagtctct
Target sequence
aggagcctgagctcctcgcctggctaatttttttactttgtatagagacagggtctacctgtgttgc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate