Basic Information
VIS ID
TVIS30015809
Fusion event
HIV-PLB1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
28846760/28623893 (Hg38)
End
28846787/28623893 (Hg38)
Orient
+
Location type
Intronic
Target gene
PLB1
Nearest miRNA
hsa-mir-1301/Upstream/627444; hsa-mir-10b/Downstream/3908260;
Nearest TSS
ENST00000437798/Upstream/3221; ENST00000436775/Downstream/6693;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/56827, chr2-CpG: 141/Downstream/127453
Upstream sequence
cgtcacatgttaaaaggatataatttggctgggtgcggtggctcacgcctctaatcccagcactttgggaggccaaggtaggcagattgcccaggagttg
Downstream sequence
ccctgtctctaccaaaaatacaaaaaattagccgggcatggtggcatggacctgtagtcccagctactcggaaggctgagatgggaggatcacttgagct
Target sequence
gagaccagtctgagcaacttggtgaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate