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TVIS30015814
Basic Information
VIS ID
TVIS30015814
Fusion event
HIV-EIF2AK2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
37375237/37148094 (Hg38)
End
37374737/37148094 (Hg38)
Orient
-
Location type
Intronic
Target gene
EIF2AK2
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-124-3p
;
hsa-mir-877-5p
;
hsa-mir-15b-5p
;
hsa-mir-4769-3p
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-6867-5p
;
hsa-mir-574-5p
;
hsa-mir-202-5p
;
hsa-mir-7158-5p
;
hsa-mir-6832-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-5196-3p
;
hsa-mir-665
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-298
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-4649-3p
;
hsa-mir-3664-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-4695-5p
;
hsa-mir-510-5p
;
hsa-mir-34b-3p
;
hsa-mir-495-5p
;
hsa-mir-1252-3p
;
hsa-mir-3646
;
hsa-mir-4762-5p
;
hsa-mir-5586-5p
;
hsa-mir-3606-3p
;
hsa-mir-4282
;
hsa-mir-4698
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-8063
Nearest miRNA
hsa-mir-1301/Upstream/1676608; hsa-mir-10b/Downstream/10229581;
Nearest TSS
ENST00000437798/Upstream/288;
ENST00000470216/Downstream/8938;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/63344
,
chr2-CpG: 31/Downstream/8664
Upstream sequence
ACTGCACAATAAAGTTAATTTCTCCAAAATTTTCTACTTTAAAAACTCAACTTggccaggtgtggtggctcacgcctataatcccagccaaggtgggcgg
Downstream sequence
atcacctgagctcaggagttcgagaccagcctgggcaacatggcgaaaccccatctcAATTTTGAAATTGTTTTAAAAAATAAAGGAAAGAAAAAAAACT
Target sequence
agaataatggtttccagcttcatccatgtccctacaaaggacatgaactcatcattttttatggctgcCATATCATTTTTTATAGCAACCTACCTCCTATCATGTGGAGGTCCTGAATTAGGCAGTTCTTGATATTTAAGTACTACTCCCTGCTTCTGACGGTATGTATTAAGTTCCTCCATGAAGAAACCTGCTGAAAGATCACCAGCCATTTCTTCTTCCCGTATCCTACAATGGAAGAGACATTTGAATGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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