Basic Information
VIS ID
TVIS30015814
Fusion event
HIV-EIF2AK2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.2
Reference genome
End
37374737/37148094 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1301/Upstream/1676608; hsa-mir-10b/Downstream/10229581;
Upstream sequence
ACTGCACAATAAAGTTAATTTCTCCAAAATTTTCTACTTTAAAAACTCAACTTggccaggtgtggtggctcacgcctataatcccagccaaggtgggcgg
Downstream sequence
atcacctgagctcaggagttcgagaccagcctgggcaacatggcgaaaccccatctcAATTTTGAAATTGTTTTAAAAAATAAAGGAAAGAAAAAAAACT
Target sequence
agaataatggtttccagcttcatccatgtccctacaaaggacatgaactcatcattttttatggctgcCATATCATTTTTTATAGCAACCTACCTCCTATCATGTGGAGGTCCTGAATTAGGCAGTTCTTGATATTTAAGTACTACTCCCTGCTTCTGACGGTATGTATTAAGTTCCTCCATGAAGAAACCTGCTGAAAGATCACCAGCCATTTCTTCTTCCCGTATCCTACAATGGAAGAGACATTTGAATGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate