VISDB Viral Integration Site DataBase

VIS ID

TVIS30015821

Fusion event

HIV-SPTBN1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr2

Cytoband

p16.2

Reference genome

Start

End

54818830/54591518 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA2S ; FRA2D ; FRA2H

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-192-5p ; hsa-mir-93-5p ; hsa-mir-1301-3p ; hsa-mir-615-3p ; hsa-mir-589-3p ; hsa-mir-193b-3p ; hsa-mir-423-3p ; hsa-mir-331-3p ; hsa-mir-195-5p ; hsa-mir-26a-5p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-145-5p

Nearest miRNA

hsa-mir-1301/Upstream/742313; hsa-mir-10b/Downstream/1391449;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/32686, chr2-CpG: 30/Downstream/37443

Nearest cancer related gene

SPTBN1(TSG, No orient, 0)

Upstream sequence

ATTGCTGTCTCTTACTTAGGGGGTAGGCCATTATCTTAGCACAATTGAAGAGCCTGATAGAAAATATTACTGGGTTATACGTGCAGGTTCAGACTACTTG

Downstream sequence

GAACTGTGGCATATGGTGAATATAGTTGTGTTTAGCACTCTGTGCTGAGGGTATTGCAGAAAGATGCCGTACAATCATTTCCATCATGCAGTGCCCTTCT

Target sequence

AAAAGTAAAAGAAAGATTCCTTCTCTTAAGCCAGGTATAAATTCAGTCTTTAGGGGAACAATGAATAGGGTCTTTTGACAGTTCCTGATTCTATGTTTCCTTTTTTTTCCATCCGGAGATGTTCCATGCCTTCAGGCTTTCCTTCATTCCTGGCTCCCATCCCTTTCCATAACCA