Basic Information
VIS ID
TVIS30015824
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
64251088/64023954 (Hg38)
End
64251041/64023954 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/1818037; hsa-mir-10b/Downstream/316793;
Nearest TSS
ENST00000437798/Upstream/4882; ENST00000438115/Downstream/64292;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/4195, chr2-CpG: 112/Downstream/119800
Nearby gene
VPS54(No orient, 4874)
Upstream sequence
ttggcagcatttattttcttgcatttacagactgagagccctggctccttgctggctcaaggctgccctcagattttagaggccacctgcagttcctcac
Downstream sequence
cctgtgggtttccctaacacagctgtttacttcatcagccagtgaggagtgtctttAAAGTCTCTAAAGTGAATCTGCTAGCCAAATggagtgatatcct
Target sequence
ggctcaaggctgccctcagattttagaggccacctgcagttcctcac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate