Basic Information
VIS ID
TVIS30015827
Fusion event
HIV-LINC00309 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
64430121/64202987 (Hg38)
End
64430211/64202987 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC00309
Nearest miRNA
hsa-mir-1301/Upstream/1997070; hsa-mir-10b/Downstream/137760;
Nearest TSS
ENST00000437798/Upstream/58533; ENST00000436950/Downstream/2498;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/58310, chr2-CpG: 99/Downstream/250988
Upstream sequence
TCGTTTAATTGATTTCACATTCACAACTATAGTGGCGCTGAAAGCCAGTGAAAAATTTTCCCCGAAATAAAAAATATTCCTTGTTAGGAATTAAGAATTG
Downstream sequence
TTTGAAAGTAGCTTAAATGTAACGATTGTAATTACTATTTGTGTATACAAAATGAATTTAAGGACTATTCTAATTGCTAGGAAACATGCAAACCTAAAAA
Target sequence
AATACCTGCTATTTTCCCAGAAGAAAAATGGAAAGAATACTTCTTGAGAGTATGTTGACAGTCTGTCTAGAATTTTCAAGTGTAGGAGAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate