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TVIS30015828
Basic Information
VIS ID
TVIS30015828
Fusion event
HIV-RAB1A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
65328189/65101055 (Hg38)
End
65328362/65101055 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
RAB1A
miRNAs that regulate target gene
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-19b-3p
;
hsa-mir-16-5p
;
hsa-mir-221-3p
;
hsa-mir-3158-5p
;
hsa-mir-3124-3p
;
hsa-mir-3678-3p
;
hsa-mir-2467-3p
;
hsa-mir-3185
;
hsa-mir-4691-3p
;
hsa-mir-4719
;
hsa-mir-449b-3p
;
hsa-mir-544a
;
hsa-mir-17-3p
;
hsa-mir-1205
;
hsa-mir-1184
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-3065-5p
;
hsa-mir-4778-5p
;
hsa-mir-648
;
hsa-mir-376c-3p
;
hsa-mir-338-5p
;
hsa-mir-7-2-3p
;
hsa-mir-7-1-3p
;
hsa-mir-19a-3p
;
hsa-mir-466
;
hsa-mir-4672
;
hsa-mir-3941
;
hsa-mir-873-5p
;
hsa-mir-3159
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-8485
;
hsa-mir-329-3p
;
hsa-mir-541-5p
;
hsa-mir-7156-3p
;
hsa-mir-34a-3p
;
hsa-mir-4762-3p
;
hsa-mir-3679-3p
;
hsa-mir-4680-5p
;
hsa-mir-4539
;
hsa-mir-130b-5p
;
hsa-mir-15b-5p
;
hsa-mir-101-5p
Nearest miRNA
hsa-mir-1301/Upstream/575490; hsa-mir-10b/Downstream/1257194;
Nearest TSS
ENST00000437798/Upstream/30326;
ENST00000471552/Downstream/29031;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/44020
,
chr2-CpG: 99/Downstream/28546
Upstream sequence
accaacatggtgaaaccccatctctactaaaaatacaaaaattagccaggcacagtagtacacgcctgtaataccagctactcgggaggctgaggcatga
Downstream sequence
TCGTCTGCCCAAAAGCCTCAGTTATCTCTCTCTGCATAACCCTACTTACTCCCCAGCCCCAAGGTCATGTGGCATTTATTCATCCTTCAGTTTTGAGCTC
Target sequence
gaatcacttgaacccgggaggtgggagttatagtgagctgagatcatgccactgtactccagcctggatgacagagctagactccatctcaaaaaaaaaaagaaaaagaaagaaaTGCTGAATTCTTGTAAATCTCTAAATGACCTTTACTCCCATGCCTGAGCCGTTACTAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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