Basic Information
VIS ID
TVIS30015830
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
68679737/68452605 (Hg38)
End
68679992/68452605 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/2094277; hsa-mir-10b/Downstream/651077;
Nearest TSS
ENST00000437798/Upstream/64663; ENST00000529851/Downstream/14653;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/132626, chr2-CpG: 98/Downstream/14310
Nearby gene
FBXO48(No orient, 9767)
Upstream sequence
tgccatattctagactttgaaattttttgtaagagtgaaaactttcaaaataaaaCATTTAGGGAGAAAGCACGTTTAAAAATATATAATAAAAGTCTGA
Downstream sequence
GTATAATTTTGTCATATTAAAAGTAAATCAAAATGAGCAAACTGGGAAACCAGCAGCTGGGTTTTTTTCCCCTACAAGGCACAGAAGACCCATAGCAGAA
Target sequence
GAGAGAAAAAAAAAAGTTGAACTGATGAAAAAAGTAGGCCATACACAGGAAAACAATGGCAAAAGCAGTCCTTTTTATTTTCTTCACTAACCAATGAGAATAAAGACAGGAAATTGTGCTCAATCTACTTGTTAGGCAACAAAAAAACACAACCACAGCAATAAGTGGGGGAGATTCTCACGTGTGATTTTTAGAAAGCTTCTTTTATGGTTTTACATATTTTCTATCAGGATTTCATTGTGTGACAAATGGACT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate