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TVIS30015831
Basic Information
VIS ID
TVIS30015831
Fusion event
HIV-GFPT1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
69601395/69374263 (Hg38)
End
69601457/69374263 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
;
FRA2E
Target gene
GFPT1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-590-3p
;
hsa-mir-335-5p
;
hsa-mir-34a-5p
;
hsa-mir-302c-5p
;
hsa-mir-888-3p
;
hsa-mir-4768-5p
;
hsa-mir-6833-3p
;
hsa-mir-1180-5p
;
hsa-mir-7114-3p
;
hsa-mir-485-5p
;
hsa-mir-3529-3p
;
hsa-mir-3065-5p
;
hsa-mir-4420
;
hsa-mir-181b-3p
;
hsa-mir-181b-2-3p
;
hsa-mir-302d-5p
;
hsa-mir-2277-3p
;
hsa-mir-302b-5p
;
hsa-mir-4526
;
hsa-mir-3660
;
hsa-mir-383-3p
;
hsa-mir-1304-3p
;
hsa-mir-3680-5p
;
hsa-mir-34b-3p
;
hsa-mir-2113
;
hsa-mir-4477b
;
hsa-mir-218-5p
;
hsa-mir-3912-5p
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-4452
;
hsa-mir-183-3p
;
hsa-mir-769-5p
;
hsa-mir-4786-5p
;
hsa-mir-4461
;
hsa-mir-3163
;
hsa-mir-646
;
hsa-mir-541-5p
;
hsa-mir-561-3p
;
hsa-mir-548at-5p
;
hsa-mir-4282
;
hsa-mir-330-3p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-4463
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-6873-3p
;
hsa-mir-1229-3p
;
hsa-mir-452-3p
;
hsa-mir-6862-3p
;
hsa-mir-6784-3p
;
hsa-mir-6511b-3p
;
hsa-mir-6511a-3p
;
hsa-mir-1281
;
hsa-mir-3620-3p
;
hsa-mir-6865-3p
;
hsa-mir-141-5p
;
hsa-mir-4762-3p
;
hsa-mir-4303
;
hsa-mir-5689
;
hsa-mir-27b-5p
;
hsa-mir-6751-3p
;
hsa-mir-1199-5p
;
hsa-mir-5586-3p
;
hsa-mir-6782-3p
;
hsa-mir-140-3p
;
hsa-mir-122-5p
;
hsa-mir-129-5p
;
hsa-mir-3135b
;
hsa-mir-3194-3p
;
hsa-mir-3652
;
hsa-mir-4280
;
hsa-mir-431-5p
;
hsa-mir-4430
;
hsa-mir-4755-3p
;
hsa-mir-5007-5p
;
hsa-mir-504-3p
;
hsa-mir-5691
;
hsa-mir-6805-3p
;
hsa-mir-8055
;
hsa-mir-924
Nearest miRNA
hsa-mir-1301/Upstream/270508; hsa-mir-10b/Downstream/878655;
Nearest TSS
ENST00000437798/Upstream/10671;
ENST00000418066/Downstream/12985;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/66620
,
chr2-CpG: 47/Downstream/12813
Upstream sequence
TTAGCATAATTATGTCAAGTATGTGAAAAAACGTGAAGTTAGATTCTGTCTTTCAAACATTTCAAACCGTTTAAAGGCAATGGAACTTTTTCAAGGGGGA
Downstream sequence
ttttttgagacagagtctcactctgtcacgcaggatggagtccagcagcacgatctcggctcacggcaagctccgcctcccgggttcacaccattctcct
Target sequence
GTTTCTCATAAGTATAAAAAACTAAACATGTCAAAATACACATTTATAAttttttctttttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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