Basic Information
VIS ID
TVIS30015833
Fusion event
HIV-AAK1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
End
69821156/69593867 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-3663-3p ; hsa-mir-7848-3p ; hsa-mir-155-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-622 ; hsa-mir-148a-5p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6731-3p ; hsa-mir-892c-5p ; hsa-mir-1276 ; hsa-mir-6839-3p ; hsa-mir-3679-3p ; hsa-mir-6826-3p ; hsa-mir-629-5p ; hsa-mir-4261 ; hsa-mir-875-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-4308 ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-587 ; hsa-mir-145-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-4272 ; hsa-mir-580-5p ; hsa-mir-3662 ; hsa-mir-377-3p ; hsa-mir-216b-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3671 ; hsa-mir-372-5p ; hsa-mir-888-5p ; hsa-mir-8070 ; hsa-mir-6759-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-3653-5p ; hsa-mir-371a-5p ; hsa-mir-4314 ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-764 ; hsa-mir-500a-5p ; hsa-mir-2355-5p ; hsa-mir-6793-3p ; hsa-mir-889-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6513-3p ; hsa-mir-6878-3p ; hsa-mir-378a-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6778-3p ; hsa-mir-212-5p ; hsa-mir-1224-3p ; hsa-mir-6813-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-3978 ; hsa-mir-497-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548t-3p ; hsa-mir-6776-3p
Nearest miRNA
hsa-mir-1301/Upstream/490112; hsa-mir-10b/Downstream/659051;
Upstream sequence
tggagaaatcatcacaaacatttattacctgtttctcactcaatgctgggatgcctcagaggctactagagtgtacaatgctacttccctcactcattag
Downstream sequence
ACTCATTAATAAAAACAAGAAAGAATAAAAAGACTGAGGGAGGGGACAGGGTCTCTCCTAAGGTACAAGTTGGAATCCGCTTTTGTGAGCAATTTCTACT
Target sequence
gtagctccagactgtaatccttttaactcctctgccagctttaacatttctgtctttgaccttagcggctcttgccattgttctctactgtcaggttggcgtccttctccattttaatgtattgcttttaatTCAACAGTAAATCAAAAGTATAAGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate