Basic Information
VIS ID
TVIS30015836
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
70326850/70099718 (Hg38)
End
70327036/70099718 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2E
Nearest miRNA
hsa-mir-1301/Upstream/995963; hsa-mir-10b/Downstream/153200;
Nearest TSS
ENST00000437798/Upstream/9997; ENST00000422380/Downstream/25599;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/11360, chr2-CpG: 19/Downstream/24465
Nearby gene
PCBP1(No orient, 10516)
Upstream sequence
aaaattaaaaaattaaaaattaaaaaaatttagccaggtgccatggtgtgcgcctgtggtcccagctactcgggaggctgaggcaggagaattgcttgaa
Downstream sequence
tagatatataatttgtaaatattttctcccgttctgtgagttgtcataactttcttaataatgtcctttgaagcacaaaagtttttaattttgatgaaga
Target sequence
cccgggaagtggaggtttcagtgagccgagatcacgctatcacaattccagcctgggtgacagagcgagaatccatctcaaaacaacaaaataaaataaaatcctttgcccatttaaaaaattaagttgtctttttattattgcgttgtaagagttctatatatattctatatactagaaccttat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate