Basic Information
VIS ID
TVIS30015852
Fusion event
HIV-SNRPG integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
70514207/70287075 (Hg38)
End
70513993/70287075 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2E
Target gene
SNRPG
miRNAs that regulate target gene
hsa-mir-320a
Nearest miRNA
hsa-mir-1285-2/Upstream/34070; hsa-mir-10b/Downstream/4803737;
Nearest TSS
ENST00000437798/Upstream/12317; ENST00000445084/Downstream/5701;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/28528, chr2-CpG: 52/Downstream/6261
Upstream sequence
AGCTCACAAGGGAATATACCTGAAAGACAAGTCAATTTACATGAAACTTGGGGGTACAGTGTGGTATCTGGAGACTCTAAACTGTTTTTTCAGTCATAAC
Downstream sequence
TATTGATTTGCTTTTCAAAATACAGTAATGAAAAAGTATCTGAAATAAGTAATAACACAAACCTTGGAAAGAATGGTATGTAAAAAAATTAAACAGGCAG
Target sequence
TAGAATGAAAATTTATTTGTAAAAATAAGGGCTGAGAGGAAAATCTTGGGGTATCTAGAAAATGTTTTTAAAAGGACTTGGCTACTAATCATGCTGGCAGCCTTATTCAACAGAAGCTCACAAGGGAATATACCTGAAAGACAAGTCAATTTACATGAAACTTGGGGGTACAGTGTGGTATCTGGAGACTCTAAACTGTTTTTTCAGTCATAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate