Basic Information
VIS ID
TVIS30015858
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
102907183/102290723 (Hg38)
End
102907018/102290723 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2A
Nearest miRNA
hsa-mir-1285-2/Upstream/981189; hsa-mir-10b/Downstream/141566;
Nearest TSS
ENST00000437798/Upstream/103409; ENST00000447231/Downstream/20779;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/39356, chr2-CpG: 54/Downstream/64935
Nearby gene
IL1RL1(No orient, 20778)
Upstream sequence
TCTTTAACTTTACAGGGTTGTAAAATAGCTATGCCTGAATTGTTAGTTAAAACCCCATTTTTTTTTTTAGAGAAAACAATGATCCTTAGACTCACTTACT
Downstream sequence
AGAAATATGTTCTAGtttttttataaaaataaaataaaataaatatttttattataaaataataaatatttttataataaaaataaaaataaaataaaaa
Target sequence
TCTGTTGTGTTTTGCATGAGATAGAAACAAAAATACCTCCCATTGGTCAGTTTTCTACAAGATAATCTTTAACTTTACAGGGTTGTAAAATAGCTATGCCTGAATTGTTAGTTAAAACCCCATTTTTTTTTTTAGAGAAAACAATGATCCTTAGACTCACTTACT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate