Basic Information
VIS ID
TVIS30015862
Fusion event
HIV-PTPN4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
End
120637856/119880136 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/6158768; hsa-mir-10b/Downstream/7543401;
Upstream sequence
CGGGAAAGAATGGAGTCAAACAGGTTCACCAGGTTAAACACCGTTTACTTTTAGCAGGTGCTAGCATCATTAGAACTGAATTTTTCCAATTCCTGAGATA
Downstream sequence
tgcctctTGGTTAAATGAGTATGTAAGTAAAATTTGGCAAGTATAGGCATTATTTATGTCAGATTTACAATATTATGGCAAGGATATGCATGACCTTTAA
Target sequence
CATATACtaggcaagttgatactactttcttcttacaaatgtagaaactaaggctcagccacattttaactaatttgcccaagatcacaggctagttttgcctaggacttgaattctggtttctacttttaacagttaagttct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate