Basic Information
VIS ID
TVIS30015867
Fusion event
HIV-DARS integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.3
Reference genome
End
136724789/135967431 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-128-1/Upstream/301953; hsa-mir-10b/Downstream/4619195;
Upstream sequence
GGAAGTGTAAGTAAGTTTTTAGGAAGAATAGTGCTGAAATAATTATTTTGTGCCAGTGCCTTCCACATGGTACGTATAAAATTTGAAAGGAATGACAGAC
Downstream sequence
ATTCCAATTACTCTTTCAATATGCAGACTTATGCTCATATGTTTCACGCTTGAAAGAAACTAATTTTAAGCATATCATTAAGGTAAGAAATTTCTCCTTG
Target sequence
TTGTATTAATCAATTAGGGATTAAAACAACAAAGATCTCAACGTTCTGAAGTATTTTCCACTTATTGCTTCCCCTGAAATGTTCCTGCATAGATTTAAGTTGAAGTTATTTTGGAAGTGTAAGTAAGTTTTTAGGAAGAATAGTGCTGAAATAATTATTTTGTGCCAGTGCCTTCCACATGGTACGTATAAAATTTGAAAGGAATGACAGAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate