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TVIS30015867
Basic Information
VIS ID
TVIS30015867
Fusion event
HIV-DARS integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
136725001/135967431 (Hg38)
End
136724789/135967431 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
;
FRA2F
Target gene
DARS
miRNAs that regulate target gene
hsa-mir-651-5p
;
hsa-mir-7977
;
hsa-mir-4266
;
hsa-mir-342-3p
;
hsa-mir-383-3p
;
hsa-mir-1228-3p
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-1305
;
hsa-mir-607
;
hsa-mir-3671
;
hsa-mir-627-3p
;
hsa-mir-3691-3p
;
hsa-mir-5584-5p
;
hsa-mir-6873-5p
;
hsa-mir-1264
;
hsa-mir-1972
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-5089-5p
;
hsa-mir-6728-5p
;
hsa-mir-769-3p
;
hsa-mir-450b-3p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-5187-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-4755-3p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-5693
;
hsa-mir-6715b-5p
;
hsa-mir-4269
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-6895-5p
;
hsa-mir-5582-5p
;
hsa-mir-4692
;
hsa-mir-4514
;
hsa-mir-1182
;
hsa-mir-1207-5p
;
hsa-mir-129-5p
;
hsa-mir-1304-5p
;
hsa-mir-1827
;
hsa-mir-215-3p
;
hsa-mir-4763-3p
;
hsa-mir-6765-5p
;
hsa-mir-6773-3p
;
hsa-mir-6808-5p
;
hsa-mir-6812-3p
;
hsa-mir-6893-5p
;
hsa-mir-8055
;
hsa-mir-940
Nearest miRNA
hsa-mir-128-1/Upstream/301953; hsa-mir-10b/Downstream/4619195;
Nearest TSS
ENST00000437798/Upstream/46878;
ENST00000444406/Downstream/13120;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/90772
,
chr2-CpG: 70/Downstream/17686
Upstream sequence
GGAAGTGTAAGTAAGTTTTTAGGAAGAATAGTGCTGAAATAATTATTTTGTGCCAGTGCCTTCCACATGGTACGTATAAAATTTGAAAGGAATGACAGAC
Downstream sequence
ATTCCAATTACTCTTTCAATATGCAGACTTATGCTCATATGTTTCACGCTTGAAAGAAACTAATTTTAAGCATATCATTAAGGTAAGAAATTTCTCCTTG
Target sequence
TTGTATTAATCAATTAGGGATTAAAACAACAAAGATCTCAACGTTCTGAAGTATTTTCCACTTATTGCTTCCCCTGAAATGTTCCTGCATAGATTTAAGTTGAAGTTATTTTGGAAGTGTAAGTAAGTTTTTAGGAAGAATAGTGCTGAAATAATTATTTTGTGCCAGTGCCTTCCACATGGTACGTATAAAATTTGAAAGGAATGACAGAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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