Basic Information
VIS ID
TVIS30015868
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
147263128/146505560 (Hg38)
End
147263148/146505560 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2K
Nearest miRNA
hsa-mir-128-1/Upstream/5918875; hsa-mir-10b/Downstream/2824718;
Nearest TSS
ENST00000437798/Upstream/590470; ENST00000450667/Downstream/332189;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1981072, chr2-CpG: 49/Downstream/81673
Nearby gene
PABPC1P2(No orient, 81496)
Upstream sequence
CCCTCCCTAGAAAACGGCTGCATTTCACCTTTCTGTTTGagagtaactaaccatcctattttgcctgggagtgggggcaatcctgggacagggaacttcc
Downstream sequence
atagacaatttgggactatttggtAATTTTATACACTTCCCAAAGGCAGCTTCTGGGATGCCCAATAAGGCTCATTAAGAATTATGTCATGAATAATTTC
Target sequence
ctactaaaatcaggaaagtc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate