Basic Information
VIS ID
TVIS30015870
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
158529917/157673405 (Hg38)
End
158529993/157673405 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-128-1/Upstream/6304994; hsa-mir-10b/Downstream/1513430;
Nearest TSS
ENST00000437798/Upstream/44400; ENST00000604340/Downstream/62600;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/44222, chr2-CpG: 120/Downstream/202268
Nearby gene
ACVR1(No orient, 63040)
Upstream sequence
ATTTGCACTTCTACTGTACTGTATTTAGATGAAGTCAAAGTTCATGAATGAggccgggcacggtggctcatgcctgtaatcccagcactttgggaggctg
Downstream sequence
tacaaaaaattagccaggtgtggtggtgggcacctgtaatcccagcctactcgggaggctgaggcaggagaattgcttgaacccgggaggcagaggttgc
Target sequence
aggcaggcagatcacctgaggtcaggagtttgggaccggcctggccaacatggtgaaaccccgtctctactaaaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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