Basic Information
VIS ID
TVIS30015879
Fusion event
HIV-TANK integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
162044337/161187826 (Hg38)
End
162044278/161187826 (Hg38)
Orient
-
Location type
Intronic
Target gene
TANK
miRNAs that regulate target gene
hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4459 ; hsa-mir-4468 ; hsa-mir-455-3p ; hsa-mir-4756-3p ; hsa-mir-500a-3p ; hsa-mir-5186 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-128-1/Upstream/779944; hsa-mir-10b/Downstream/7395117;
Nearest TSS
ENST00000437798/Upstream/8173; ENST00000470324/Downstream/35574;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/27006, chr2-CpG: 142/Downstream/50123
Nearest cancer related gene
TANK(TSG, No orient, 0)
Upstream sequence
cctaacagacatatgtaaaaaccccagcaacaacagaatacacatttgctcaagggcatatggagcattctctgggagaggccattaaaaatgacttaat
Downstream sequence
aaatttaaaaagattaaaatcatgctaagtatattttctaatcacaatgaaatgaaactagaagtcagcaaaagaaaaagtgggaaattcacaactatgt
Target sequence
acatttgctcaagggcatatggagcattctctgggagaggccattaaaaatgacttaat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate