Basic Information
VIS ID
TVIS30015880
Fusion event
HIV-DHRS9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
169947170/169090660 (Hg38)
End
169946943/169090660 (Hg38)
Orient
-
Location type
Intronic
Target gene
DHRS9
Nearest miRNA
hsa-mir-128-1/Upstream/507642; hsa-mir-10b/Downstream/6076973;
Nearest TSS
ENST00000437798/Upstream/9553; ENST00000432133/Downstream/10083;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/200165, chr2-CpG: 119/Downstream/271144
Upstream sequence
AACCTAAGAAAAAATAAATTACATTTTAAGTCCACTAATAGAGCTTTTAAAAATCTTATGGTGAAGAGTTTTATAAAATGAATAAATACTTCCTTATATT
Downstream sequence
ATATATTCCTGGTAGGAAAATAAATCAAATTTAGGAAACGACTATTCATATACTGGTTTGCTGTAcaggtggtccctgacttgcaatgttaaacatgact
Target sequence
TGGGAAATAATCTTTTTTAATTTTAGTACAAGTCATATACCTTACAGAATATTTCAAGGTCAAGCTAACTTGCATTTTTAGTAAAATATATTTCAAACTTTACAATAATAACGTTGCTAGAAAGCAGAACCTAAGAAAAAATAAATTACATTTTAAGTCCACTAATAGAGCTTTTAAAAATCTTATGGTGAAGAGTTTTATAAAATGAATAAATACTTCCTTATATT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate