Basic Information
VIS ID
TVIS30015885
Fusion event
HIV-LINC01934 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
182050613/181185886 (Hg38)
End
182050501/181185886 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
LINC01934
Nearest miRNA
hsa-mir-10b/Upstream/1324978; hsa-mir-1244-1/Downstream/119707;
Nearest TSS
ENST00000437798/Upstream/12162; ENST00000646009/Downstream/17470;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/204687, chr2-CpG: 119/Downstream/271148
Nearby gene
MIR4437(No orient, 119706)
Upstream sequence
TCATTTCTCCATTCACTTGCTTGcatgaggacagaggccttgccatgtttgcccgacattactccttagcatctgacacagttcatggcacgcagagaat
Downstream sequence
aaagaaaaatatttattgcataaGCAAGGGAATGACATATATAGGTCTTTGCTCCTTTTCCTACTCTTTATACCTAATTCCAAGCTCCTCCTGAACTAGA
Target sequence
ACCATTCTGTAATCATTTCTCCATTCACTTGCTTGcatgaggacagaggccttgccatgtttgcccgacattactccttagcatctgacacagttcatggcacgcagagaat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate